Biotin NovaTag Resin

Biotin NovaTag™ resin is an ideal tool for the synthesis of peptides labeled iwth biotin. As the biotin moiety is incorporated into the linker, its use eliminates the problems associated with biotin-labeling of peptides, namely poor solubility and sluggish coupling kinetics of biotin and its derivatives. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the peptide labeled with biotin. For a recent applications see [1, 2].



The product number for this product was previously 04-12-3901.

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Analysis Note

Color (visual): white to light yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.35 – 0.65 mmol/gSwelling Volume (in DMF): lot specific resultThe polymer metrix is copoly (styrene – 1% DVB), 100 – 200 mesh.

Legal Information

NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage
Replaces: 04-12-3901

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